written and first recorded by Jimmie Rodgers (1930).
Hit versions by Bill Monroe (1940), The Fendermen (US #5/UK #32/CND #2 1960).
Also recorded by Woody Guthrie (1944), Odetta (1956).
From the wiki: “‘Mule Skinner Blues’ is a classic country song written by Jimmie Rodgers. The song was first recorded by Rodgers in 1930 and has been recorded by many artists since then, acquiring the de facto title ‘Mule Skinner Blues’ after Rodgers named it ‘Blue Yodel #8’.